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Ultra Low Dose Coronary Artery Calcium Screening (CCS) Using Dual Source CT Prospective ECG Gating

IRB Number: 14680

IRB Expiration Date: 03/31/2009

Purpose of Study

The purpose of this research study is to determine if an ultra-low radiation coronary calcium scan using the most advanced CT machine called the ¿dual-source CT¿ (DSCT), can provide comparable results to the standard low radiation protocol coronary calcium scan using the same DSCT.

Coronary calcium screening is a well established method of measuring calcium build-up in the coronary arteries. Physicians always want to perform a diagnostic test using the least amount of radiation possible while still maintaining excellent diagnostic performance. The DSCT scanner has been proven to have excellent quality in measuring coronary calcium with a decrease in dose from conventional Coronary Calcium Scan cameras (multi-slice CT). Researchers in this study are trying to see if they can duplicate the same accuracy as the standard protocol coronary calcium scan using DSCT scanning with an ultra-low radiation DSCT scan.

Eligibility Requirements

Eligible subjects are those that meet all of the following inclusion criteria:

  • Are scheduled to undergo coronary calcification screening at Cedars-Sinai
  • Are 18 years of age or older, and
  • Are able and willing to give consent to participate in the research project

Research Procedures

After you sign informed consent to be included in the lower radiation Coronary Calcium Scan study (this study), you will undergo your clinical standard care scan using DSCT.

Immediately after the clinical scan a second scan will be performed without asking you to
move from the imaging table. This will be the very low dose research scan. The process
of getting the research scan, from beginning to finish, will add approximately 2-4 minutes
to your regular clinic visit.

Contact Information

Nancy Zambrana
Study Coordinator
S. Mark Taper Foundation Imaging Center
Cedars-Sinai Medical Center
Phone: (310) 423-3763
E-mail: nancy.zambrana@cshs.org
 
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